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Before taking Rasagiline, caution should be exercised in case of: Any liver problems; Any suspicious skin changes (treatment with Rasagiline may possibly increase the risk of skin cancer).
Impulse control disorders include the development of unusual behaviours where the impulse, urges or cravings to carry out certain harmful or detrimental activities to oneself or others cannot be resisted. In patients taking rasagiline and/or other medicines used to treat Parkinson's disease, behaviours such as compulsions, obsessive thoughts, addictive gambling, excessive spending, impulsive behaviour and an abnormally high sex drive or an increase in sexual thoughts or feelings have been observed. The dose may need to be adjusted or stopped (see Side Effects).
Rasagiline may cause drowsiness and may cause sudden sleep onset during day time activities, especially if other dopaminergic medicinal products are being taken. For further information, refer to Driving and using machines as follows.
Driving and using machines: Parkinson's disease as well as the treatment with rasagiline may influence the ability to drive and operate machines. Rasagiline can cause dizziness or drowsiness; it can also cause episodes of sudden sleep onset.
This might be enhanced if other medicines to treat the symptoms of Parkinson's disease or medicines which can cause drowsiness are being taken, or if alcohol is consumed while taking rasagiline. In case of somnolence and/or episodes of sudden sleep onset before or while taking rasagiline, patients should not drive or operate machinery (see as previously mentioned).
Use in Children: There is no relevant use of rasagiline in children and adolescents. Therefore, Rasagiline is not recommended for use under the age of 18.
